How does IgA affect human immune system?

September 2, 2009 | By admin In Skin Conditions |
human disease
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What factors to cause such a disease to human?

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3 Comments so far

  1. gkakkasseri on September 5th, 2009

    IgA Nephropathy
    IgA nephropathy is a kidney disorder caused by deposits of the protein immunoglobulin A (IgA) inside the glomeruli (filters) within the kidney. These glomeruli (the singular form is glomerulus) normally filter wastes and excess water from the blood and send them to the bladder as urine. The IgA protein prevents this filtering process, leading to blood and protein in the urine and swelling in the hands and feet. This chronic kidney disease may progress over a period of 10 to 20 years. If this disorder leads to end-stage renal disease, the patient must go on dialysis or receive a kidney transplant.

    The IgA protein, an antibody, is a normal part of the body’s immune system, the system that protects against disease. We do not know what causes IgA deposits in the glomeruli. But, since IgA nephropathy may run in families, genetic factors probably contribute to the disease.

    Kidney disease usually cannot be cured. Once the tiny filtering units are damaged, they cannot be repaired. Treatment focuses on slowing the progression of the disease and preventing complications. One complication is high blood pressure, which further damages glomeruli. A class of medicines called ACE inhibitors protects kidney function not only by lowering blood pressure but also by reducing the loss of protein into the urine.

    Some patients may benefit from limiting protein in their diet to reduce the buildup of waste in the blood. Patients with IgA nephropathy often have high cholesterol. Reducing cholesterol—through diet, medication, or both—appears to help slow the progression of IgA nephropathy.

    Corticosteroids may suppress the production of IgA but can have harmful side effects. In preliminary studies, fish oil supplements containing omega 3 fatty acids also appear to slow the progression of the kidney disease. A new immunosuppressive agent called mycophenolate mofetil (MMF) is also being tested.

    For More Information

    American Kidney Fund
    6110 Executive Boulevard, Suite 1010
    Rockville, MD 20852
    Phone: 1–800–638–8299 or 301–881–3052
    Email:
    Internet:

    IgA Nephropathy Support Network
    9 G Street, Apt. B
    Turners Falls, MA 01376
    Phone: 413–863–8663

    National Heart, Lung, and Blood Institute Health Information Center
    P.O. Box 30105
    Bethesda, MD 20824–0105
    Phone: 301–592–8573
    Email:
    Internet:

    National Kidney Foundation
    30 East 33rd Street
    New York, NY 10016
    Phone: 1–800–622–9010 or 212–889–2210
    Email:
    Internet:

    ——————————————————————————–

    Additional Information on IgA Nephropathy

    The National Kidney and Urologic Diseases Information Clearinghouse collects resource information on kidney and urologic diseases for the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Reference Collection. This database provides titles, abstracts, and availability information for health information and health education resources. The NIDDK Reference Collection is a service of the National Institutes of Health.

    To provide you with the most up-to-date resources, information specialists at the clearinghouse created an automatic search of the NIDDK Reference Collection. To obtain this information, you may view the results of the automatic search on IgA Nephropathy.

    If you wish to perform your own search of the database, you may access and search the NIDDK Reference Collection database online.

    ——————————————————————————–

    National Kidney and Urologic Diseases Information Clearinghouse
    3 Information Way
    Bethesda, MD 20892–3580
    Email:

    The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The NIDDK is part of the National Institutes of Health under the U.S. Department of Health and Human Services. Established in 1987, the Clearinghouse provides information about diseases of the kidneys and urologic system to people with kidney and urologic disorders and to their families, health care professionals, and the public. The NKUDIC answers inquiries, develops and distributes publications, and works closely with professional and patient organizations and Government agencies to coordinate resources about kidney and urologic diseases.

    Publications produced by the Clearinghouse are carefully reviewed by both NIDDK scientists and outside experts.

    This publication is not copyrighted. The Clearinghouse encourages users of this publication to duplicate and distribute as many copies as desired.

    ——————————————————————————–

    NIH Publication No. 03–4571
    August 2003

    [Top]

    Kidney and Urologic Diseases Home | Kidney and Urologic Diseases A-Z | Statistics | Clinical Trials | in Spanish | Additional Resources | Order Publications | About Us |

    Contact Us | NIDDK Health Information

    The NKUDIC Clearinghouse is a service of the National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health

    National Kidney and Urologic Diseases Information Clearinghouse
    3 Information Way
    Bethesda, MD 20892–3580
    Phone: 1–800–891–5390
    Fax: 703–738–4929
    Email:

    Privacy | Disclaimer | Accessibility

  2. Xangoman on September 7th, 2009

    Go to and listen to the audio links there on mangosteen juice and rebuilding the immune system on a cellular and molecular level. Dr. John Edwards discusses many uses of mangosteen and it’s benefits to the human body.

    To obtain mangosteen juice go to discovery.com Order it securely right on the site It’s all natural, no side effects and tastes great fully patented

  3. John C on September 8th, 2009

    LISTEN TO THIS GUY HE SOUNDS SMART:

    gkakkasseri
    2 weeks ago

    Report Abuse
    IgA Nephropathy
    IgA nephropathy is a kidney disorder caused by deposits of the protein immunoglobulin A (IgA) inside the glomeruli (filters) within the kidney. These glomeruli (the singular form is glomerulus) normally filter wastes and excess water from the blood and send them to the bladder as urine. The IgA protein prevents this filtering process, leading to blood and protein in the urine and swelling in the hands and feet. This chronic kidney disease may progress over a period of 10 to 20 years. If this disorder leads to end-stage renal disease, the patient must go on dialysis or receive a kidney transplant.

    The IgA protein, an antibody, is a normal part of the body’s immune system, the system that protects against disease. We do not know what causes IgA deposits in the glomeruli. But, since IgA nephropathy may run in families, genetic factors probably contribute to the disease.

    Kidney disease usually cannot be cured. Once the tiny filtering units are damaged, they cannot be repaired. Treatment focuses on slowing the progression of the disease and preventing complications. One complication is high blood pressure, which further damages glomeruli. A class of medicines called ACE inhibitors protects kidney function not only by lowering blood pressure but also by reducing the loss of protein into the urine.

    Some patients may benefit from limiting protein in their diet to reduce the buildup of waste in the blood. Patients with IgA nephropathy often have high cholesterol. Reducing cholesterol—through diet, medication, or both—appears to help slow the progression of IgA nephropathy.

    Corticosteroids may suppress the production of IgA but can have harmful side effects. In preliminary studies, fish oil supplements containing omega 3 fatty acids also appear to slow the progression of the kidney disease. A new immunosuppressive agent called mycophenolate mofetil (MMF) is also being tested.

    For More Information

    American Kidney Fund
    6110 Executive Boulevard, Suite 1010
    Rockville, MD 20852
    Phone: 1–800–638–8299 or 301–881–3052
    Email:
    Internet:

    IgA Nephropathy Support Network
    9 G Street, Apt. B
    Turners Falls, MA 01376
    Phone: 413–863–8663

    National Heart, Lung, and Blood Institute Health Information Center
    P.O. Box 30105
    Bethesda, MD 20824–0105
    Phone: 301–592–8573
    Email:
    Internet:

    National Kidney Foundation
    30 East 33rd Street
    New York, NY 10016
    Phone: 1–800–622–9010 or 212–889–2210
    Email:
    Internet:

    ——————————…

    Additional Information on IgA Nephropathy

    The National Kidney and Urologic Diseases Information Clearinghouse collects resource information on kidney and urologic diseases for the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Reference Collection. This database provides titles, abstracts, and availability information for health information and health education resources. The NIDDK Reference Collection is a service of the National Institutes of Health.

    To provide you with the most up-to-date resources, information specialists at the clearinghouse created an automatic search of the NIDDK Reference Collection. To obtain this information, you may view the results of the automatic search on IgA Nephropathy.

    If you wish to perform your own search of the database, you may access and search the NIDDK Reference Collection database online.

    ——————————…

    National Kidney and Urologic Diseases Information Clearinghouse
    3 Information Way
    Bethesda, MD 20892–3580
    Email:

    The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The NIDDK is part of the National Institutes of Health under the U.S. Department of Health and Human Services. Established in 1987, the Clearinghouse provides information about diseases of the kidneys and urologic system to people with kidney and urologic disorders and to their families, health care professionals, and the public. The NKUDIC answers inquiries, develops and distributes publications, and works closely with professional and patient organizations and Government agencies to coordinate resources about kidney and urologic diseases.

    Publications produced by the Clearinghouse are carefully reviewed by both NIDDK scientists and outside experts.

    This publication is not copyrighted. The Clearinghouse encourages users of this publication to duplicate and distribute as many copies as desired.

    ——————————…

    NIH Publication No. 03–4571
    August 2003

    [Top]

    Kidney and Urologic Diseases Home | Kidney and Urologic Diseases A-Z | Statistics | Clinical Trials | in Spanish | Additional Resources | Order Publications | About Us |

    Contact Us | NIDDK Health Information

    The NKUDIC Clearinghouse is a service of the National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health

    National Kidney and Urologic Diseases Information Clearinghouse
    3 Information Way
    Bethesda, MD 20892–3580
    Phone: 1–800–891–5390
    Fax: 703–738–4929
    Email:

    Privacy | Disclaimer | Accessibility

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